What does the research say about pulmonary artery wedge pressure?

Pulmonary artery wedge pressure

There are 2 papers on pulmonary artery wedge pressure in aging research: 1 trial and 1 observational study in people. The newest story, Nov 8, 2026: “Semaglutide lowered pressure in a heart failure group with obesity”.

Biomarker

2 papers study it3 more mention it1 finding

2 new papers in 30 daysSee all 5 papers on pulmonary artery wedge pressure

Human trial1
Humans1

Interventions

Exercise

upin humans1

1 study

Exercise increases pulmonary artery wedge pressure in humans (11±3 to 22±5 mm Hg (p<0.01)).
“End-expiratory PAWP at baseline was 11±3 mm Hg and increased to 22±5 mm Hg at early-light exercise (p<0.01).”
Human trialcycle ergometry2 minn = 28
The pulmonary artery wedge pressure response to sustained exercise is time-variant in healthy adults
Heart (British Cardiac Society)Jan 13, 2016

Latest

2 papers in 12 months

Nature MedicineNov 8

Semaglutide lowered pressure in a heart failure group with obesity

Among patients with obesity and heart failure with preserved ejection fraction, exercise pressure fell 9.8 millimeters of mercury with semaglutide versus a 0.9 rise with…Among patients with obesity and heart failure with preserved ejection fraction, exercise pressure fell 9.8 millimeters of mercury with semaglutide versus a 0.9 rise with placebo.

Randomized trial · 81 peopleSemaglutide

Paper

HeartJan 15

The pulmonary artery wedge pressure response to sustained exercise is time-variant in healthy adults

Study of 28 peopleMechanisms

Paper

Nature MedicineNov 8

Semaglutide improved heart filling in obesity-related heart failure

Semaglutide improved how much the heart’s upper left chamber stretched by 5.7 percentage points versus placebo over 52 weeks in a 49-person trial substudy.Semaglutide improved how much the heart’s upper left chamber stretched by 5.7 percentage points versus placebo over 52 weeks in a 49-person trial substudy.

Randomized trial · 49 peopleSemaglutide