Proteostasis factors and UPR components

1 paper1 finding

Cells1

Upstream

1

Glial aging

downin mouse cells1

1 study

Glial aging decreases proteostasis factors and UPR components in mouse cells.
“glia exhibited broad downregulation of proteostasis factors and UPR components, independent of neuronal presence.”
Cellsindependent of neuronal presenceglial cell
Proteostasis and Unfolded Protein Response Dynamics in Human Neuron and Mouse Glia Co-culture Reveal Cell-Specific Aging Responses
bioRxiv : the preprint server for biology13 Aug 2025Preprint

Latest

bioRxiv20 Aug

Proteostasis and Unfolded Protein Response Dynamics in Human Neuron and Mouse Glia Co-culture Reveal Cell-Specific Aging Responses

Preprint: experiments in human cellsER unfolded protein response