PROSPER

Biomarker

1 paper2 findings

  • Humans1

Associations

2

CV death or myocardial infarction

upin humans1

1 study
  1. PROSPER raises the risk of CV death or myocardial infarction in humans (adjHR 1.62, 95% CI 1.35-1.92).

    “those in the highest quintile had a significantly elevated risk of CV death or MI (adjHR 1.62, 95% CI 1.35-1.92”

    Humanshighest vs lowest quintile, adjusting for age, sex, race, ethnicity, diabetes, and BMI13.6 yearsn = 50,689

    A PROtein Signature of PlatelEt Reactivity (PROSPER) Associated with Cardiovascular Events

    AHA Scientific Sessions 2025 abstract3 Nov 2025

More on CV death or myocardial infarction

Platelet activity

upin humans1

1 study
  1. PROSPER is associated with platelet activity in humans (r=0.53, p=0.002).

    “PROSPER was significantly associated with a composite of platelet activity (r=0.53, p=0.002”

    Humansindependent validation cohortn = 33

    A PROtein Signature of PlatelEt Reactivity (PROSPER) Associated with Cardiovascular Events

    AHA Scientific Sessions 2025 abstract3 Nov 2025

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