medRxiv
Genetic dementia risk linked to thinking levels and decline
An observational analysis of 11,518 US adults used 26 years of data to distinguish genetic links involving preexisting thinking ability from those involving age-related…An observational analysis of 11,518 US adults used 26 years of data to distinguish genetic links involving preexisting thinking ability from those involving age-related decline.
Preprint: cohort · 11,518 peopleAlzheimer's disease and related dementias
Who was studied11,518 ancestrally diverse US adults, 26 years
What changedGenetic scores were associated with dementia risk through cognitive decline for some traits and through premorbid cognitive differences for others
The catchEffects of changing diabetes risk, physical activity, or other traits were not measured