European Journal of Pharmacology
The diabetes medication Canagliflozin attenuates alcoholic liver disease by reducing hepatic lipid accumulation via SIRT1-AMPK-mTORC1 signaling pathway
Experiments in miceCanagliflozin
Papers on PPARα expression
7 papers
Saturday, February 8
Saturday, June 29
Wednesday, July 10
EBioMedicine
Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy
Study in peopleInterventions
Monday, February 12
Journal of the American Society of Nephrology
Impairment of PPARα and the Fatty Acid Oxidation Pathway Aggravates Renal Fibrosis during Aging
Experiments in ratsFatty acid β-oxidation
Tuesday, November 28
Journal of Interferon & Cytokine Research
Interleukin-6 Affects Aging-Related Changes of the PPARα-PGC-1α Axis in the Myocardium
Experiments in miceMechanisms
Thursday, November 3
FASEB Journal
PPARα-ATGL pathway improves muscle mitochondrial metabolism: implication in aging
Experiments in ratsOxidative phosphorylation
Friday, January 8
Hormone Molecular Biology and Clinical Investigation
Practical prospects for boosting hepatic production of the "pro-longevity" hormone FGF21
ReviewInterventions