Polyglucosan bodies

Biomarker

2 papers2 findings

  • Animals2

Effects

1

Cognitive function

no changein animals1

1 study
  1. Polyglucosan bodies have no effect on cognitive function.

    “direct behavioral testing demonstrated that cognition remains intact despite age-related PGB burden.”

    Animalshippocampus

    The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus

    Cell systems2 Feb 2026

Associations

1

PGB1

upin animals1

1 study
  1. PGB1 is associated with polyglucosan bodies.

    “genetic mapping through quantitative trait locus analysis identified a major locus (Pgb1) that modulates hippocampal PGB burden.”

    Animalshippocampus

    The Smarcal1-Usp37 locus modulates glycogen aggregation in astrocytes of the aged hippocampus

    Cell systems2 Feb 2026

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