Platelet aggregation response

There is 1 paper on platelet aggregation response in aging research: 1 observational study in people.

Biomarker

1 paper studies it3 findings

See all 1 papers on platelet aggregation response

“platelet aggregation response was positively associated with increased amyloid in the precuneus (β = 0.047, p = 0.020)”
Association of Platelet Aggregation With Markers of Alzheimer Disease Pathology in Middle-Aged Participants of the Framingham Heart StudyNeurology2025doi:10.1212/wnl.0000000000214314
  • Humans1

Associations

3

MRI-based cortical thickness signature of Alzheimer disease risk

downin humans1

1 study
  1. Platelet aggregation response is associated with MRI-based cortical thickness signature of Alzheimer disease risk in humans (Dementia-free participants) (β = -0.002).

    “platelet aggregation response was negatively associated with the MRI-based cortical thickness signature of AD risk (β = -0.002, p < 0.035)”

    HumansDementia-free participantscerebral cortexn = 256

    Association of Platelet Aggregation With Markers of Alzheimer Disease Pathology in Middle-Aged Participants of the Framingham Heart Study

    Neurology

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Rhinal tau PET uptake

upin humans1

1 study
  1. Platelet aggregation response is associated with rhinal tau PET uptake in humans (Dementia-free participants in the lowest tertile of adenosine diphosphate response) (Rhinal β = 0.077; entorhinal β = 0.066; temporal global β = 0.063; cortical β = 0.064).

    “platelet aggregation response was positively associated with increased amyloid in the precuneus (β = 0.047, p = 0.020) and tau in the rhinal (β = 0.077, p = 0.012)”

    HumansDementia-free participants in the lowest tertile of adenosine diphosphate responserhinal region

    Association of Platelet Aggregation With Markers of Alzheimer Disease Pathology in Middle-Aged Participants of the Framingham Heart Study

    Neurology

More on Rhinal tau PET uptake

Precuneus amyloid PET uptake

upin humans1

1 study
  1. Platelet aggregation response is associated with precuneus amyloid PET uptake in humans (Dementia-free participants in the lowest tertile of adenosine diphosphate response) (β = 0.047).

    “platelet aggregation response was positively associated with increased amyloid in the precuneus (β = 0.047, p = 0.020)”

    HumansDementia-free participants in the lowest tertile of adenosine diphosphate responseprecuneus

    Association of Platelet Aggregation With Markers of Alzheimer Disease Pathology in Middle-Aged Participants of the Framingham Heart Study

    Neurology

More on Precuneus amyloid PET uptake

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