Plasma proteomics

Biomarker

1 paper

  • Humans1

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Alzheimer's & Dementia

Diet-related blood proteins are linked to Alzheimer's risk

Higher scores on a brain-healthy diet were associated with lower odds of Alzheimer's disease, with an odds ratio of 0.75, in 206 participants.Higher scores on a brain-healthy diet were associated with lower odds of Alzheimer's disease, with an odds ratio of 0.75, in 206 participants.

Cross-sectional study of 10,228 peopleMechanisms
bioRxiv

Blood protein clock tracks shifts in health risks over time

In an observational study of 4,100 people, accelerated blood protein aging tracked worsening kidney function, blood lipid imbalances, and a higher risk of death.In an observational study of 4,100 people, accelerated blood protein aging tracked worsening kidney function, blood lipid imbalances, and a higher risk of death.

Preprint: cohort study of 4,100 peopleBiomarkers
Geriatrics & Gerontology International

An 11-protein blood score tracks incident dementia risk

In over 36,000 UK Biobank participants, the signature raised Harrell's C-index from 0.798 to 0.862, carrying a hazard ratio of 2.645 per standard deviation increase.In over 36,000 UK Biobank participants, the signature raised Harrell's C-index from 0.798 to 0.862, carrying a hazard ratio of 2.645 per standard deviation increase.

Cohort study of 36,696 peopleDementia