Higher scores on a brain-healthy diet were associated with lower odds of Alzheimer's disease, with an odds ratio of 0.75, in 206 participants.Higher scores on a brain-healthy diet were associated with lower odds of Alzheimer's disease, with an odds ratio of 0.75, in 206 participants.
A three-region model scored 0.81 versus 0.79 for a whole-brain model on a measure of how well it ranked death risk.A three-region model scored 0.81 versus 0.79 for a whole-brain model on a measure of how well it ranked death risk.
Blood proteins statistically accounted for 0.5 to 50.7% of the risk associated with biological aging measures.Blood proteins statistically accounted for 0.5 to 50.7% of the risk associated with biological aging measures.
In an observational study of 4,100 people, accelerated blood protein aging tracked worsening kidney function, blood lipid imbalances, and a higher risk of death.In an observational study of 4,100 people, accelerated blood protein aging tracked worsening kidney function, blood lipid imbalances, and a higher risk of death.
Links to heart attacks were stronger at lower kidney function for 154 blood proteins and at higher function for 22.Links to heart attacks were stronger at lower kidney function for 154 blood proteins and at higher function for 22.
In over 36,000 UK Biobank participants, the signature raised Harrell's C-index from 0.798 to 0.862, carrying a hazard ratio of 2.645 per standard deviation increase.In over 36,000 UK Biobank participants, the signature raised Harrell's C-index from 0.798 to 0.862, carrying a hazard ratio of 2.645 per standard deviation increase.