medRxiv
Nerve-cell injury marker linked to death risk at ages 92–107
Higher marker levels were linked to higher mortality, with reported hazard ratios (relative death-rate measures) of 1.21 to 1.38 across three cohorts.Higher marker levels were linked to higher mortality, with reported hazard ratios (relative death-rate measures) of 1.21 to 1.38 across three cohorts.
Preprint: cohort · 559 peopleBiomarkers
Who was studied559 Dutch and Danish adults aged 92-107, up to 16 years
What changedDeath from any cause was more likely with higher blood NfL levels across cohorts (hazard ratios 1.21-1.38)
The catchKidney impairment, inflammation, and hidden vascular disease could influence biomarker levels and confound the association