Peak-width skeletonized mean diffusivity

Biomarker1 paper2 findings

  • Humans1

Associations

2

Cognitive decline

upin humans1

1 study
  1. Peak-width skeletonized mean diffusivity predicts cognitive decline in humans.

    Humanswhite matter5.6 yearsn = 2,800

    Brain diffusion scans predict dementia risk and mental decline · Imaging neuroscience (Cambridge, Mass.) · 6 Oct 2026

Cognitive decline →

Dementia

upin humans1

1 study
  1. Peak-width skeletonized mean diffusivity predicts dementia in humans (C-statistic: 0.886).

    Humanswhite mattermedian follow-up of 9.8 yearsn = 5,230

    Brain diffusion scans predict dementia risk and mental decline · Imaging neuroscience (Cambridge, Mass.) · 6 Oct 2026

Dementia →

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Imaging NeuroscienceHumans

Brain diffusion scans predict dementia risk and mental decline

Among 5,230 adults aged 45 and older followed for a median 9.8 years, one brain diffusion marker best predicted cognitive decline, while two best…Among 5,230 adults aged 45 and older followed for a median 9.8 years, one brain diffusion marker best predicted cognitive decline, while two best predicted dementia risk.