Overall Aging Gap

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Incident diseases and all-cause mortality

upin humans1HR 1.15–1.49

1 study
  1. Overall Aging Gap predicts incident diseases and all-cause mortality in humans (HRs 1.15–1.49 per s.d. across 15 endpoints; all-cause mortality HR 1.41 per s.d.).

    “broadly stratified all 15 prespecified prospective endpoints, including 14 incident diseases and all-cause mortality (hazard ratios 1.15–1.49 per s.d.; mortality HR = 1.41 per s.d.).”

    Humansper s.d. higher Overall Aging Gapn = 67,130

    MRI reveals the hierarchical organization of abdominal biological aging from shared burden to disease-specific organ engagement

    medRxiv12 May 2026Preprint

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