Osteoporosis Self-Assessment Tool

Biomarker

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  • Humans7

Associations

4

Osteoporosis

upin humans4

4 studies
  1. Osteoporosis Self-Assessment Tool predicts osteoporosis in humans (AUC 0.7339 (95% CI, 0.7121-0.7556)).

    “The AUCs were 0.7339 (95% CI, 0.7121-0.7556) for OST”

    Humansmalesn = 2,824

    Performance of USPSTF-recommended osteoporosis risk assessment tools in identifying osteoporosis in older men: a multicentre retrospective study

    Frontiers in endocrinology

  2. Osteoporosis Self-Assessment Tool predicts osteoporosis in humans (AUC 0.79 to 0.85).

    “For discrimination of femoral neck osteoporosis, AUC values were excellent for OST (range, 0.79 [95% CI, 0.65-0.93] to 0.85 [95% CI, 0.74-0.96]), higher for OST than FRAX”

    Humansfemoral neckfemalesn = 4,607

    Race and Ethnicity and Fracture Prediction Among Younger Postmenopausal Women in the Women's Health Initiative Study

    JAMA internal medicine

  3. Osteoporosis Self-Assessment Tool predicts osteoporosis in humans (sensitivity 86.49% at cutoff 2.5).

    “To differentiate normal participants from those with osteoporosis, the cutoff value with optimal sensitivity was 2.5. At such a cutoff value, the test sensitivity was 86.49%.”

    Humanscutoff 2.5femalesn = 2,969

    Use of the Osteoporosis Self-Assessment Tool as a Screening Tool for Osteoporosis in Saudi Postmenopausal Women

    Cureus

  4. Osteoporosis Self-Assessment Tool predicts osteoporosis in humans (AUC 0.702, sensitivity 95.7%, specificity 33.6%).

    “OST index ≤2 predicted osteoporosis with a sensitivity of 95.7% and a specificity of 33.6% and an area under the curve for a receiver operating characteristic curve of 0.702.”

    HumansOSTA index <= 2malesn = 257

    Utility of Osteoporosis Self-Assessment Tool as a Screening Tool for Predicting Osteoporosis in Indian Men

    Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry

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Mortality

upin humans1downin humans1HR 0.66

2 studies
  1. Osteoporosis Self-Assessment Tool is associated with mortality in humans (aOR 2.08, 95% CI 1.44-3.01).

    “OST Tertile 3 remained independently associated with increased in-hospital mortality (adjusted odds ratio 2.08; 95 % CI, 1.44-3.01) compared with Tertile 1.”

    Humansacute myocardial infarction

    Impact of osteoporosis risk on in-hospital mortality in older patients with acute myocardial infarction: Insight from Tokyo CCU network database

    International journal of cardiology. Cardiovascular risk and prevention

  2. Osteoporosis Self-Assessment Tool lowers the risk of mortality in humans (HR 0.66, 95% CI 0.48-0.90).

    “Multivariate analysis revealed that OST tertiles 3 was associated with decreased risk of all-cause mortality (hazard ratio, 0.66; 95% confidence interval, 0.48-0.90)”

    Humansmen undergoing transcatheter aortic valve replacementmalesn = 1,339

    Impact of osteoporotic risk in men undergoing transcatheter aortic valve replacement: a report from the LAPLACE-TAVI registry

    Cardiovascular intervention and therapeutics

Major osteoporotic fractures

mixedin humans1

1 study
  1. Osteoporosis Self-Assessment Tool predicts major osteoporotic fractures in humans (AUC 0.53 to 0.62).

    “The AUC values for OST were 0.62 (95% CI, 0.56-0.69) for Asian, 0.53 (95% CI, 0.50-0.57) for Black, 0.58 (95% CI, 0.54-0.62) for Hispanic, and 0.55 (95% CI, 0.54-0.56) for White women.”

    Humans10 yearsfemalesn = 67,169

    Race and Ethnicity and Fracture Prediction Among Younger Postmenopausal Women in the Women's Health Initiative Study

    JAMA internal medicine

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Osteopenia

upin humans1

1 study
  1. Osteoporosis Self-Assessment Tool predicts osteopenia in humans (sensitivity 81.04% at cutoff 3.5).

    “To differentiate normal individuals from those with osteopenia, the cutoff value with optimal sensitivity was 3.5. At such a cutoff value, the test sensitivity was 81.04%.”

    Humanscutoff 3.5femalesn = 2,969

    Use of the Osteoporosis Self-Assessment Tool as a Screening Tool for Osteoporosis in Saudi Postmenopausal Women

    Cureus

More on Osteopenia

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