Oral microbiome risk score

Oral microbiome risk score improves upper gastrointestinal cancer risk discrimination in humans (AUC 0.63 to 0.69).

“significantly improved the clinical covariate model (increasing the area under the receiver operating characteristic curve [AUC] from 0.63 to 0.69; DeLong P = 0.015)”

Humansdiscrimination of UGIC continuumsalivan = 416

Salivary microbiome exhibits stage-associated network topological shifts in upper gastrointestinal carcinogenesis

Research Square·11 Oct 2026Preprint