Nucleosome-related proteins

1. Frailty is associated with nucleosome-related proteins in humans (p < 0.05, log2-fold change ±0.5).

   “∼40 proteins elevated in frail individuals, including nucleosome-related proteins (H2B, H3C1, H2AC3, H3-4).”

   Humansplasman = 18

   Identifying Biomarkers of Frailty Through an Integrated Multi-omics Analysis

   GSA 2025 abstract·31 Dec 2025

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