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neutrophil-to-HDL cholesterol ratio

Biomarker

1 paper2 findings

  • Humans1

Associations

1

Cognitive impairment

upin humans1OR 1.14

1 study

  1. neutrophil-to-HDL cholesterol ratio predicts cognitive impairment in humans (AUC = 0.602).

    “NHR outperformed traditional biomarkers (AUC = 0.602)”

    Humansn = 2,355

    Immunometabolic biomarkers of brain aging: Nonlinear association between neutrophil-to-HDL cholesterol ratio and cognitive decline in older adults

    Brain, behavior, and immunity8 Sep 2025

  2. neutrophil-to-HDL cholesterol ratio raises the risk of cognitive impairment in humans (adjusted OR = 1.14, 95 % CI: 1.01-1.24, P = 0.031).

    “Higher NHR was significantly associated with cognitive impairment (adjusted OR = 1.14, 95 % CI: 1.01-1.24, P = 0.031).”

    Humansn = 2,355

    Immunometabolic biomarkers of brain aging: Nonlinear association between neutrophil-to-HDL cholesterol ratio and cognitive decline in older adults

    Brain, behavior, and immunity8 Sep 2025

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