What does the research say about Neoantigenic peptides?

Neoantigenic peptides

There is 1 paper on neoantigenic peptides in aging research: none in people yet.

1 paper studies it1 more mentions it2 findings

“Notably, 60 neoantigenic peptides were confirmed using proteomic data from elderly individuals”

Aging-related alternative splicing events

upin humans1

1 study

Aging-related alternative splicing events are associated with neoantigenic peptides in humans (confirmed with proteomic data from elderly individuals) (60 neoantigenic peptides confirmed).
“Notably, 60 neoantigenic peptides were confirmed using proteomic data from elderly individuals”
Humansconfirmed with proteomic data from elderly individualsn = 60
Aging-related alternative splicing drive neoantigen emergence revealed by transcriptome analysis of 1,255 human blood samples
Frontiers in agingMay 9, 2025

HLA-C14:02ALLELE

upin silico1

1 study

HLA-C14:02ALLELE is associated with neoantigenic peptides in silico (neoantigen prediction from aging-related alternative splicing events) (most neoantigenic peptides among alleles).
“with the HLA-C14:02 allele presenting the most neoantigenic peptides.”
In siliconeoantigen prediction from aging-related alternative splicing events
Aging-related alternative splicing drive neoantigen emergence revealed by transcriptome analysis of 1,255 human blood samples
Frontiers in agingMay 9, 2025