NADase activity
1 paper1 finding
- Animals1
Upstream
1CD38
upin mice1
1 study
CD38
upin mice1
CD38 increases NADase activity in mice (essentially absent in CD38 deficient mice).
“NADase activity in the plasma membrane, mitochondria, sarcoplasmic reticulum, and nuclei is essentially absent in most tissues from CD38 deficient mice.”
Animalsin CD38-deficient mice
Regulation of intracellular levels of NAD: a novel role for CD38
Biochemical and biophysical research communications15 May 2006
Latest
Nature Metabolism
Senescent cells promote tissue NAD⁺ decline during ageing via the activation of CD38⁺ macrophages
Experiments in animalsCellular senescence
Biochemical and Biophysical Research Communications
The NADase CD38 is induced by factors secreted from senescent cells providing a potential link between senescence and age-related cellular NAD⁺ decline
Experiments in cellsCellular senescence
Biochemical and Biophysical Research Communications
Regulation of intracellular levels of NAD: a novel role for CD38
Experiments in miceCD38