N-terminal tau fragment
Biomarker1 paper2 findings
- Human trial1
Interventions
2Cocoa extract
no changein humans1High certainty
1 study
Cocoa extract
no changein humans1High certainty
Cocoa extract has no effect on N-terminal tau fragment in humans (-0.7%; 95% CI: -7.1% to 6.1%; p = 0.83).
Human trial2 years
Effect of a multivitamin and cocoa flavanol extract on changes in neurofilament light, N-terminal tau fragment, and oligomeric amyloid-β levels in COSMOS-clinic · Journal of Alzheimer's disease : JAD · 23 Sep 2026
Multivitamin-multimineral
no changein humans1High certainty
1 study
Multivitamin-multimineral
no changein humans1High certainty
Multivitamin-multimineral has no effect on N-terminal tau fragment in humans (3.7%; 95% CI: -3% to 10.8%; p = 0.29).
Human trial2 years
Effect of a multivitamin and cocoa flavanol extract on changes in neurofilament light, N-terminal tau fragment, and oligomeric amyloid-β levels in COSMOS-clinic · Journal of Alzheimer's disease : JAD · 23 Sep 2026