Muscle proteomic age gap

Muscle proteomic age gap is associated with age-Related Multiple Sclerosis Severity Score in humans (β=0.17, 95% CI 0.10–0.24).

“higher muscle age gap was associated with greater global Age-Related Multiple Sclerosis Severity Score (β=0.17, 95% CI 0.10-0.24, P<0.001, FDR<0.001)”

HumansMultiple sclerosis

Proteomic Age Acceleration in Multiple Sclerosis Precedes Symptom Onset and Associates with Severity

medRxiv : the preprint server for health sciences·20 Apr 2026Preprint