There is 1 paper on multiple TP53 mutation burden in aging research: 1 observational study in people.
1 paper studies it1 finding
- Humans1
Upstream
1ERCC6L2 disease
upin humans1
1 study
ERCC6L2 disease
upin humans1
ERCC6L2 disease is linked with higher multiple TP53 mutation burden in humans (compared with sporadic TP53-mutated myeloid neoplasia).
“The burden of multiple TP53 mutations exceeded that of sporadic TP53-mutated myeloid neoplasia”
Humanscompared with sporadic TP53-mutated myeloid neoplasia
medRxivPreprint
Latest
1 paper in 12 monthsmedRxiv
Intense TP53 pathway selection drives clonal evolution from bone marrow failure to leukemia in ERCC6L2 disease
Preprint: cohort study of 29 peopleBones and joints