Monoclonal B-cell lymphocytosis

1 paper1 finding

Associations

1

Frailty

upin humans1

1 study

Monoclonal B-cell lymphocytosis raises the risk of frailty in humans.
“pre-malignant aging processes-such as clonal hematopoiesis of indeterminate potential (CHIP) and monoclonal B-cell lymphocytosis (MBL)-contribute to an underlying frailty predisposition, which is exacerbated by CLL.”
Review
Frailty and chronic lymphocytic leukemia: navigating challenges to improve outcomes
Expert review of hematologyMar 17, 2026

Funding

1 grant since 2022

National Institute on AgingUS$464.2k

Prevalence, etiology, and clinical implications of low count monoclonal B-cell lymphocytosis (MBL)
National Institute on AgingMayo Clinic RochesterUS$464.2k2018–2023

Latest

2 in 12 months

Seminars in Cancer BiologyAug 10

Clonal dynamics on the road to hematological malignancy (MBL, MGUS, CH)

ReviewMechanisms

Expert Review of HematologyMar 17

Frailty and chronic lymphocytic leukemia: navigating challenges to improve outcomes

Systematic reviewBiomarkers

GeroScienceOct 15

Genomic instability and genetic heterogeneity in aging: insights from clonal hematopoiesis (CHIP), monoclonal gammopathy (MGUS), and monoclonal B-cell lymphocytosis (MBL)

ReviewDNA damage response

Cancer Metastasis ReviewsJan 10

Mesenchymal stromal cell senescence in haematological malignancies

ReviewMechanisms

BloodApr 30

Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes

ReviewBlood and immune system