Mitral annulus calcification

1. Mitral annulus calcification raises the risk of infective endocarditis in humans (HR 1.03, 95%CI 1.01-1.05).

   “Each 100 AU increase in MAC was associated with a 3% increase in the risk of IE (HR 1.03, 95%CI 1.01-1.05, P = 0.011).”

   HumansDANCAVAS cohortper 100 AU increasen = 14,793

   Mitral annulus calcification and the risk of infective endocarditis: insights from DANCAVAS screening trials

   European heart journal open·8 Sep 2026

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