What does the research say about mitochondrial-associated transcriptional programs?

Mitochondrial-associated transcriptional programs

There is 1 paper on mitochondrial-associated transcriptional programs in aging research: none in people yet, 1 in animals. The newest story, Nov 3, 2026: “Age linked to shifts in heart immune-cell gene activity in mice”.

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1 new paper in 30 daysSee all 2 papers on mitochondrial-associated transcriptional programs

Animals1

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Age

downin mice1

1 study

Age decreases mitochondrial-associated transcriptional programs in mice (LPS-induced endotoxemia).
“A shared feature across these four cell populations was reduced representation of mitochondrial-associated transcriptional programs”
AnimalsLPS-induced endotoxemiacardiac extravascular leukocytes5 mg/kg body weight LPS24 h
Age linked to shifts in heart immune-cell gene activity in mice
bioRxivNov 3, 2026Preprint

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2 papers in 12 months

bioRxivNov 3

Age linked to shifts in heart immune-cell gene activity in mice

An experiment in young and aged mice found both higher and lower activity in gene programs in heart immune cells 24 hours after an inflammatory challenge.An experiment in young and aged mice found both higher and lower activity in gene programs in heart immune cells 24 hours after an inflammatory challenge.

Preprint: mouse studyImmune response

Paper

iScienceMay 15

Timed feeding linked to aligned daily gene activity in mice

Nearly four times as many mitochondrial-related gene readouts aligned across tissues with timed feeding as with unrestricted food access.Nearly four times as many mitochondrial-related gene readouts aligned across tissues with timed feeding as with unrestricted food access.

Computational studyInterventions