bioRxiv
Age linked to shifts in heart immune-cell gene activity in mice
An experiment in young and aged mice found both higher and lower activity in gene programs in heart immune cells 24 hours after an inflammatory challenge.An experiment in young and aged mice found both higher and lower activity in gene programs in heart immune cells 24 hours after an inflammatory challenge.
Preprint: mouse studyImmune response
Who was studiedYoung and aged C57BL/6 mice, 24 h, against young mice receiving LPS
What changedHeart immune-cell gene activity was both higher and lower in aged mice than in young mice after an inflammatory challenge
The catchMore severe illness in aged mice could explain their different gene activity