Microglial spontaneous Ca2+ activity

amyloid-beta plaques increase microglial spontaneous Ca2+ activity in mice (fivefold more frequent).

“they were fivefold more frequent in microglial somata near Aβ plaques than in wild-type microglia”

Animalsnear amyloid-beta plaquesbrain

Amyloid plaques and normal ageing have differential effects on microglial Ca²⁺ activity in the mouse brain

Pflugers Archiv : European journal of physiology·Nov 15, 2023