Microglial damage-evoked Ca2+ response

amyloid-beta plaques decrease microglial damage-evoked Ca2+ response in mice (less intense).

“somatic Ca2+ responses evoked by tissue damage were less intense in microglia near Aβ plaques than in wild-type microglia”

Animalsnear amyloid-beta plaquesbrain

Amyloid plaques and normal ageing have differential effects on microglial Ca²⁺ activity in the mouse brain

Pflugers Archiv : European journal of physiology·Nov 15, 2023