Experimental Gerontology
DNA marks are more variable in older rhesus macaque brains
An observational analysis of 86 hippocampus samples spanning about 3–35 years linked older age to greater variation in chemical marks on DNA.An observational analysis of 86 hippocampus samples spanning about 3–35 years linked older age to greater variation in chemical marks on DNA.
Cross-sectional studyMechanisms
Who was studiedRhesus macaque hippocampus samples
What changedDNA methylation variability increased with age in rhesus macaque hippocampus samples
The catchAge differences across samples do not measure how individual brains change over time