Mature neurons

Biomarker1 paper1 finding

  • Animals1

Interventions

1

SOX2 viral gene therapy

upin cells1Very low certainty

1 study
  1. SOX2 viral gene therapy induces mature neurons in cells.

    Cells

    Spatially Precise Neuron Formation via Hydrogel-Mediated Modulation of the Host Astrocyte Response · ACS nano · 25 Aug 2026

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bioRxivCellsPreprint

DNA polymerase kappa supports genome repair in cultured neurons

In mouse and human neurons, depleting POLK reduced repair-associated DNA synthesis and induced senescence-like stress, while augmenting POLK lowered…In mouse and human neurons, depleting POLK reduced repair-associated DNA synthesis and induced senescence-like stress, while augmenting POLK lowered DNA damage markers.