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Markers of liver aging

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Four-factor-induced reprogramming

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1 study

  1. Four-factor-induced reprogramming decreases markers of liver aging in mice.

    “partial 4F epigenetic reprogramming in old mice was able to reverse several markers of liver aging only in conjunction with the depletion of p16High cells”

    Animalsin conjunction with depletion of p16High cellsliver

    p16High senescence restricts cellular plasticity during somatic cell reprogramming

    Nature cell biology

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