AHA Scientific Sessions 2026 Abstract
Chromosome changes linked to differing clot risks in people
Large non-sex chromosome changes were linked to higher clot risk than in noncarriers, with a hazard ratio (relative risk over time) of 1.29.Large non-sex chromosome changes were linked to higher clot risk than in noncarriers, with a hazard ratio (relative risk over time) of 1.29.

Cohort studyPopulations
Who was studiedPeople without existing cancer or venous clots, against noncarriers
What changedVenous clot risk was higher with large autosomal chromosome alterations than in noncarriers (hazard ratio 1.29)
The catchCarriers were older with more heart and metabolic conditions, so residual confounding may remain
