Loss of greater than 20 kilobases of DNA from the HPRT gene
1 paper1 finding
- Cells1
Upstream
1Werner syndrome
upin human cells1+58%
1 study
Werner syndrome
upin human cells1+58%
Werner syndrome increases loss of greater than 20 kilobases of DNA from the HPRT gene in human cells (58%).
“Approximately half (58%) of the deletions in WS cells consisted of the loss of greater than 20 kilobases of DNA from the HPRT gene.”
Cellsin WS cells
Mutator phenotype of Werner syndrome is characterized by extensive deletions
Proceedings of the National Academy of Sciences of the United States of America1 Aug 1989
Latest
PNAS
Mutator phenotype of Werner syndrome is characterized by extensive deletions
Experiments in human cellsMechanisms