HPRT deletions
1 paper1 finding
- Cells1
Upstream
1Werner syndrome
upin human cells1
1 study
Werner syndrome
upin human cells1
Werner syndrome increases HPRT deletions in human cells (76% vs. 39%).
Cellsspontaneous HPRT mutations in 6-thioguanine-resistant cellsn = 89
Mutator phenotype of Werner syndrome is characterized by extensive deletions
Proceedings of the National Academy of Sciences of the United States of America1 Aug 1989
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PNAS
Mutator phenotype of Werner syndrome is characterized by extensive deletions
Experiments in human cellsMechanisms