Localized transcriptomic age

1. Neurodegenerative disease increases localized transcriptomic age in silico.

   “injury and neurodegeneration induce pronounced age acceleration, with stronger responses in older organisms and partial normalization during recovery.”

   In siliconeurodegeneration

   Multi-tissue spatial transcriptomics reveals biological age hotspots in mouse and human aging

   bioRxiv (Cold Spring Harbor Laboratory)·26 Nov 2025Preprint

More on Neurodegenerative disease

1. Injury increases localized transcriptomic age in silico.

   “injury and neurodegeneration induce pronounced age acceleration, with stronger responses in older organisms and partial normalization during recovery.”

   In silicoinjury

   Multi-tissue spatial transcriptomics reveals biological age hotspots in mouse and human aging

   bioRxiv (Cold Spring Harbor Laboratory)·26 Nov 2025Preprint