Clinical Science
Aged mice lacking an immune protein had less heart dysfunction
Experiments in isolated hearts from 21-month-old male mice found better recovery without the protein after flow through the heart stopped and restarted.Experiments in isolated hearts from 21-month-old male mice found better recovery without the protein after flow through the heart stopped and restarted.
Mouse studyMechanisms
Who was studiedAged male mice, against aged wildtype mice
What changedHearts from aged mice lacking AIM2 recovered pressure better after interrupted flow than hearts from aged mice with AIM2
The catchHeart function was measured in isolated hearts rather than living mice