Left fimbria volume

There is 1 paper on left fimbria volume in aging research: 1 observational study in people.

Biomarker

1 paper studies it2 findings

See all 1 papers on left fimbria volume

“smaller left fimbria volume correlated with poorer language-related Ecog SP performance (p = 0.009, surviving the Bonferroni-corrected threshold of p < 0.0125)”
The selective vulnerability of the left fimbria in cognitively normal APOE ε4 carriers: a localized structural correlate of high genetic risk for Alzheimer's diseaseBehavioural brain research2026doi:10.1016/j.bbr.2026.116336
  • Humans1

Interventions

1

Apoe ε4 status

downin humans1

1 study
  1. Apoe ε4 status is linked with lower left fimbria volume in humans (cognitively normal carriers; discovery in PEARL-Neuro cohort) (uncorrected p < 0.001; surviving Bonferroni-corrected threshold of p < 0.0026).

    “A selective reduction in left fimbria volume was initially discovered in the PEARL-Neuro cohort (uncorrected p < 0.001, surviving the Bonferroni-corrected threshold of p < 0.0026)”

    Humanscognitively normal carriers; discovery in PEARL-Neuro cohorthippocampus

    The selective vulnerability of the left fimbria in cognitively normal APOE ε4 carriers: a localized structural correlate of high genetic risk for Alzheimer's disease

    Behavioural brain research

More on Apoe ε4 status

Associations

1

Language-related Ecog SP performance

downin humans1

1 study
  1. Left fimbria volume is associated with language-related Ecog SP performance in ADNI cohort (p = 0.009).

    “smaller left fimbria volume correlated with poorer language-related Ecog SP performance (p = 0.009, surviving the Bonferroni-corrected threshold of p < 0.0125)”

    Humansin ADNI cohorthippocampus

    The selective vulnerability of the left fimbria in cognitively normal APOE ε4 carriers: a localized structural correlate of high genetic risk for Alzheimer's disease

    Behavioural brain research

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