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LB-positive beta cells

Biomarker

1 paper2 findings

  • Humans1

Upstream

2

Age

upin humans1

1 study

  1. Age increases LB-positive beta cells in humans (>=90% (<10 years) to >=97% (>20 years)).

    “LB-positive human beta cells (representing aged cells) increased from >or=90% (<10 years) to >or=97% (>20 years) and remained constant thereafter.”

    Humanspancreatic beta cells

    The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation

    Diabetologia24 Oct 2009

Type 2 diabetes

no changein humans1

1 study

  1. Type 2 diabetes has no effect on LB-positive beta cells in humans.

    “The proportion of human LB-positive beta cells was significantly related to age, with no apparent differences in type 2 diabetes or obesity.”

    Humanspancreatic beta cells

    The long lifespan and low turnover of human islet beta cells estimated by mathematical modelling of lipofuscin accumulation

    Diabetologia24 Oct 2009

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