Label-retaining cells

Biomarker

3 papers3 findings

  • Humans1
  • Animals2

Upstream

1

Lifespan

downin mice1

1 study
  1. Lifespan decreases label-retaining cells in mice.

    “We observed the presence and gradual decrease of LRCs in the endometrium during the lifespan of the mice.”

    Animalsduring lifespanendometrium

    Identification, characterization and co-localization of label-retaining cell population in mouse endometrium with typical undifferentiated markers

    Human reproduction (Oxford, England)21 Aug 2006

Associations

2

Donor age

downin human cells1

1 study
  1. Donor age is associated with label-retaining cells in human cells.

    “With aging, the LRCs were restricted to the periphery and were reduced.”

    Cellsdonor-derived cultured cellsretinal pigment epithelium

    Age-related reduction in the functional properties of adult stem cells located in the peripheral region of human retinal pigment epithelium

    Indian journal of ophthalmology16 Apr 2024

KRT19

upin mice1

1 study
  1. KRT19 is associated with label-retaining cells in mice.

    “Double-labelling revealed that K19-positive-cells were also [3H]thymidine-label-retaining cells, suggesting that K19 is a marker for skin stem cells of hair follicles.”

    Animalsskin

    Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage

    Journal of cell science1 May 1996

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