medRxiv
Kidney layers showed contrasting disease links in adults
Chronic kidney disease was linked to thinning across 87.7% of the left kidney’s inner region and 72.8% of the right.Chronic kidney disease was linked to thinning across 87.7% of the left kidney’s inner region and 72.8% of the right.
Preprint: cohort · 70,270 peopleBiomarkers
Who was studied70,270 UK Biobank participants, median 4.8 years
What changedKidney medulla and parenchyma thinned in chronic kidney disease, whereas the cortex thickened in diabetes and hypertension
The catchUK Biobank has healthy-volunteer selection bias and excluded more severely affected individuals