Joslin Kidney Panel proteins

1. Tirzepatide decreases Joslin Kidney Panel proteins in humans (compared with insulin glargine) (12 of 21 proteins significantly lowered).

   “Fifty-two weeks of treatment with TZP significantly lowered concentrations of 12 out of 21 circulating JKP v2 proteins in T2D patients.”

   Human trialcompared with insulin glargineplasma52 weeks

   Effect of the Dual GLP-1/GIP Receptor Agonist Tirzepatide on Circulating Proteins Associated with ESKD Risk in Patients with Type 2 Diabetes

   ADA Scientific Sessions 2026 abstract·Jun 5, 2026

More on Tirzepatide

1. Dulaglutide decreases Joslin Kidney Panel proteins in humans (type 2 diabetes and moderate-to-severe CKD).

   “After 6 months, 14 JKP proteins increased in the insulin glargine group and decreased in the dulaglutide group with statistically significant between-group differences.”

   Human trialtype 2 diabetes and moderate-to-severe CKD6 months

   Dulaglutide Effect on Proteins Associated With CKD Progression

   Kidney international reports·Jan 21, 2026

More on Dulaglutide