Iron-to-neuromelanin ratio

Age has no effect on iron-to-neuromelanin ratio in chimpanzees.

“we found that the iron-to-neuromelanin ratio remains stable with age across large neuronal populations.”

Animalsdopaminergic neurons in the substantia nigra

Single-cell quantification of the iron-neuromelanin balance in dopaminergic neurons across the lifespan

bioRxiv (Cold Spring Harbor Laboratory)·May 13, 2026Preprint