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Imidazole propionate-to-histidine ratio

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Type 2 diabetes

upin humans1HR 1.33

1 study

  1. Imidazole propionate-to-histidine ratio raises the risk of type 2 diabetes in humans (HR 1.33 [95% CI: 1.14-1.55]).

    “ImP-to-histidine ratio were positively associated with incident T2D (Hazard ratio=1.17 [95% CI:1.00-1.36] and 1.33 [1.14-1.55], respectively, comparing highest to lowest tertile)”

    Humansserum~12 yearsn = 4,632

    Diet, Gut Microbiota, and Histidine Metabolism toward Imidazole Propionate Production in Relation to Type 2 Diabetes

    ADA Scientific Sessions 2025 abstract13 Jun 2025

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