Hyperexpanded CD4+ T cell clone frequency

Hyperexpanded CD4+ T cell clone frequency is associated with rheumatoid arthritis disease activity in humans.

“Their frequency correlated with disease activity”

Humansrheumatoid arthritis

Hyperexpanded CD4 + T cell clones in rheumatoid arthritis show attenuated senescence and accumulate in afflicted joints

medRxiv·10 Jul 2026Preprint