Homeostatic dysregulation index of muscle

Biomarker

1 paper4 findings

  • Humans1

Associations

4

Oxidative phosphorylation

downin humans1

1 study
  1. Homeostatic dysregulation index of muscle is associated with oxidative phosphorylation in humans.

    “Higher HDIM derived from participants was associated with slower 400-m walk speed, lower peak VO2, muscle power, and decreased maximum rate of oxidative phosphorylation by mitochondria in muscle.”

    Humansn = 299

    Entropy of Muscle Fiber Histology Predicts Mobility in Older Adults: The Study of Muscle, Mobility, and Aging

    Aging cell23 Feb 2026

More on Oxidative phosphorylation

Muscle power

downin humans1

1 study
  1. Homeostatic dysregulation index of muscle is associated with muscle power in humans.

    “Higher HDIM derived from participants was associated with slower 400-m walk speed, lower peak VO2, muscle power, and decreased maximum rate of oxidative phosphorylation by mitochondria in muscle.”

    Humansn = 299

    Entropy of Muscle Fiber Histology Predicts Mobility in Older Adults: The Study of Muscle, Mobility, and Aging

    Aging cell23 Feb 2026

Peak VO2

downin humans1

1 study
  1. Homeostatic dysregulation index of muscle is associated with peak VO2 in humans.

    “Higher HDIM derived from participants was associated with slower 400-m walk speed, lower peak VO2, muscle power, and decreased maximum rate of oxidative phosphorylation by mitochondria in muscle.”

    Humansn = 299

    Entropy of Muscle Fiber Histology Predicts Mobility in Older Adults: The Study of Muscle, Mobility, and Aging

    Aging cell23 Feb 2026

400-m walk speed

downin humans1

1 study
  1. Homeostatic dysregulation index of muscle is associated with 400-m walk speed in humans.

    “Higher HDIM derived from participants was associated with slower 400-m walk speed, lower peak VO2, muscle power, and decreased maximum rate of oxidative phosphorylation by mitochondria in muscle.”

    Humansn = 299

    Entropy of Muscle Fiber Histology Predicts Mobility in Older Adults: The Study of Muscle, Mobility, and Aging

    Aging cell23 Feb 2026

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