HMGA2 proteoforms

1 paper1 finding

Cells1

Associations

1

Cellular senescence

upin human cells1

1 study

Cellular senescence is associated with HMGA2 proteoforms in human cells.
“We identify a rich repertoire of previously uncharacterized proteoforms, including variants of HMGA2 with N-terminal acetylation and multiple phosphorylation states (di-, tri-, and tetra-phosphorylated), implicating them as potential senescence biomarkers.”
Cellsin senescent cellsfibroblasts
Characterization of the Intact Proteomic Profile of Senescent-Associated Secretory Phenotype by Top-Down Mass Spectrometry
Analytical chemistry14 Oct 2025

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Analytical Chemistry14 Oct

Characterization of the Intact Proteomic Profile of Senescent-Associated Secretory Phenotype by Top-Down Mass Spectrometry

Experiments in human cellsSenescence-associated secretory phenotype (SASP)