Hippocampal subregion volume

1 paper studies it4 more mention it2 findings

Effects

Memory performance

mediatesin humans1

1 study

Hippocampal subregion volume mediates memory performance in humans (11% mediated for subiculum to 17% for CA composite).
“hippocampal subregions partially mediated the relationship between age and memory performance with the proportion mediated ranging from 11 % (subiculum) to 17 % (CA composite)”
HumansPartial statistical mediation of the relationship between age and memory performance; no significant mediation for the tailhippocampus
Age-associated trajectories of hippocampus subregion volumes from childhood through later adulthood
Neurobiology of agingAug 13, 2025

Age

mixedin humans1

1 study

Age is associated with hippocampal subregion volume in humans (Maximum volume in the fourth decade of life).
“The peak age at which all subregions achieved maximum volume occurred in the fourth decade of life.”
HumansHealthy individuals; CA composite, DG composite, tail and subiculumhippocampus440 female; 234 malesn = 674
Age-associated trajectories of hippocampus subregion volumes from childhood through later adulthood
Neurobiology of agingAug 13, 2025