High-frequency T-cell receptor beta clones

Biomarker

1 paper studies it1 finding

  • Humans1

Associations

1

Familial hypercholesterolemia

upin humans1

1 study
  1. Familial hypercholesterolemia is associated with high-frequency T-cell receptor beta clones in humans.

    “Consistent with reduced thymic output, FH patients showed skewing towards high-frequency T-cell receptor beta clones.”

    HumansT cell

    Inherited high cholesterol linked to lower thymus output

    European heart journal

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European Heart Journal

Inherited high cholesterol linked to lower thymus output

Patients reached the healthy comparison group’s median level on a blood-based measure of thymus output about six years earlier.Patients reached the healthy comparison group’s median level on a blood-based measure of thymus output about six years earlier.

Cross-sectional · 562 peopleBlood and immune system