Hepatic DOHH mRNA expression

1 paper2 findings

Associations

Non-alcoholic steatohepatitis

downin humans1downin mice1

1 study

Non-alcoholic steatohepatitis is associated with hepatic DOHH mRNA expression in mice.
“hepatic DOHH mRNA expression is decreased in patients and mice with non-alcoholic steatohepatitis (NASH)”
Animalsmice with non-alcoholic steatohepatitisliver
Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression
Nature communications3 Sep 2022
Non-alcoholic steatohepatitis is associated with hepatic DOHH mRNA expression in humans.
“hepatic DOHH mRNA expression is decreased in patients and mice with non-alcoholic steatohepatitis (NASH)”
Humanspatients with non-alcoholic steatohepatitisliver
Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression
Nature communications3 Sep 2022

Nature Communications3 Sep

Experiments in miceSpermidine