Hematopoietic cell transplantation-specific comorbidity index

Hematopoietic cell transplantation-specific comorbidity index is linked with lower overall survival in humans (acute myeloid leukemia receiving low-intensity therapy) (P < .05 each).

“greater comorbidity (hematopoietic cell transplantation-specific comorbidity index >3), worse cognition (Blessed Orientation-Memory-Concentration score >4), and lower European Organization for Research and Treatment of Cancer global QOL scores at baseline were significantly associated with shorter overall survival (P < .05 each)”

Humansacute myeloid leukemia receiving low-intensity therapyn = 96

Geriatric assessment for older adults receiving less-intensive therapy for acute myeloid leukemia: report of CALGB 361101

Blood advances·Apr 14, 2022

Frailty is associated with hematopoietic cell transplantation-specific comorbidity index in humans (pre-apheresis) (OR 11.9, p = 0.035).

“and also exhibit a higher number of comorbidities (HCT-CI>3: OR 11.9, p = 0.035).”

Humanspre-apheresisn = 80

At-home autologous hematopoietic cell transplant for adults with hematological malignancies. How frailty impacts and evolves during HCT procedure. An observational, longitudinal, and prospective study

Cancer treatment and research communications·Apr 3, 2025