Fibrinogen binding

Frailty is associated with fibrinogen binding in humans.

“significant differences were observed between non-frail and frail participants, with frail individuals showing increased platelet phosphatidylserine exposure, intracellular calcium mobilization, and fibrinogen binding.”

Humansfrail versus non-frail participantsplateletfemalesn = 50

Platelet reactivity in frail older women: integrating phenomic and proteomic analysis

NPJ aging·15 Oct 2026