What does the research say about fiber-bundle cross-section?

Fiber-bundle cross-section

There are 3 papers on fiber-bundle cross-section in aging research: 3 observational studies in people. The newest story, Nov 14, 2026: “Age links to brain fiber size differ among crossing fibers”.

Biomarker

3 papers study it1 more mentions it5 findings

1 new paper in 30 daysSee all 4 papers on fiber-bundle cross-section

“FC declined with age most steeply in the non-dominant fiber populations.”

Fixel-based analysis identifies selective vulnerability of non-dominant fiber populations in aging and mild cognitive impairmentBrain structure & function2026doi:10.1007/s00429-026-03224-3

Humans3

Associations

Executive function

upin humans1

1 study

Fiber-bundle cross-section is associated with executive function in humans (non-dominant fiber populations).
“higher FC was associated with better executive function.”
Humansnon-dominant fiber populationswhite matter
Age links to brain fiber size differ among crossing fibers
Brain structure & functionNov 14, 2026

Mild cognitive impairment

downin humans1

1 study

Mild cognitive impairment is associated with fiber-bundle cross-section in humans (non-dominant fiber populations; compared with cognitively unimpaired participants).
“In these populations, FC was lower in participants with mild cognitive impairment than in cognitively unimpaired participants”
Humansnon-dominant fiber populations; compared with cognitively unimpaired participantswhite matter
Age links to brain fiber size differ among crossing fibers
Brain structure & functionNov 14, 2026

Latest

2 papers in 12 months

Brain Structure & FunctionNov 14

Age links to brain fiber size differ among crossing fibers

Brain scans from 295 older adults linked age most strongly to smaller bundle size in the non-dominant groups of crossing nerve fibers.Brain scans from 295 older adults linked age most strongly to smaller bundle size in the non-dominant groups of crossing nerve fibers.

Cross-sectional · 295 peopleBiomarkers